Sarcometrics provides pre-clinical cardiac muscle evaluation of candidate pharmaceuticals, compounds, proteins, and peptides.

Sarcometrics specializes in assays of cardiac muscle function and provides quantitative assessment of excitable and demembranated cardiac tissue prepared from animal models. Immediately available assays include:

• Isometric force production of myocardium isolated and prepared from left or right ventricle
• Mimicry of ventricular pressure-volume relationship using isolated myocardium
• Contraction-relaxation function evaluated in isolated myocytes
• Fluorescence dye evaluation of intracellular Ca2+ regulation in isolated myocardium or myocytes
• Viscoelastic measurements in intact or demembranated muscle to detect myosin kinetics
• Statistical analysis of functional assays to assess inotropic effects, dose response, and cardiotoxicity