In this webinar, Stella Goulopoulou, PhD, discusses her research on pattern recognition receptors and the role of circulating cell-free mitochondrial DNA in preeclampsia pathogenesis and the related outcomes.
Preeclampsia is a multisystem hypertensive disorder of pregnancy that affects 5-8% of all pregnancies and significantly increases risk of long-term cardiovascular disease-related maternal mortality and morbidity. Preeclampsia was first described by Hippocrates in Ancient Greece. Despite advancements in biology and medicine since 400 BC, the etiology of preeclampsia remains unknown, and it is still a leading cause of maternal deaths.
This webinar will discuss Dr. Stella Goulopoulou’s research on the contribution of the placenta to circulating cell-free mitochondrial DNA in preeclampsia and the resulting vasoactive and inflammatory effects.
Key Topics Include:
- Define theoretical models of preeclampsia pathogenesis
- Describe the contribution of the placenta to circulating cell-free mitochondrial DNA in preeclampsia
- Define the inflammatory and vasoactive effects of circulating cell-free mitochondrial DNA in preeclampsia
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Resources
Presenters
Associate Professor
Lawrence Longo Center for Perinatal Biology
Loma Linda University
Dr. Goulopoulou is an Associate Professor in the Lawrence Longo Center for Perinatal Biology at Loma Linda University, Loma Linda, California. Her research program focuses on vascular physiology, with emphasis on immune and inflammatory underpinnings of female vascular dysfunction in obstetric and gynecologic disorders.
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