Prof. Julien Wist is currently the Deputy Director of the Centre for Computational and Systems Medicine at Murdoch University and head of operations and lead of the bio-/ chem-informatics team at the Australian National Phenome Centre consisting of software engineers, biostatisticians, chemometricians, and data processing experts to develop analytical pipelines for metabolic phenotyping. Wist is involved in international initiative for the development of open-source data analysis and visualisation platforms such as nmrdb.org, nmrium.org and cheminfo.org.

His research focuses on the integration of high-fidelity molecular phenotypes to create translatable methods for the clinical environment. He strives to establish a comprehensive phenotypic databank of the world population by integrating cellular, immunological, and molecular data. Prof. Wist’s research on SARS-CoV-2 infection revealed crucial markers for disease progression, including the acute phase, risk of death, and post-acute COVID 19 syndrome. More recently, Wist and his team detected and elucidated the structure of 10 new molecules for the first time in human urine and elucidated 10 of them, revealing the existence of an extended RSAD2 dependant natural antiviral pathway extending involving the Viperin enzyme to convert CTP into ddhCTP and analogs. These significant findings have led to the filing of 2 patents in collaboration with industry leaders and have been published in renowned international journals.