Improving Preclinical Decision-Making in Obesity and CKD with Translational In Vivo Phenotyping
Join us to learn how in-depth in vivo phenotyping using patient-relevant models can improve preclinical decision-making.
Opening a New Window: Stable Long-Term Imaging of Dura Mater–Transplanted Pancreatic Islets in Awake Mice
Dr. Philip Tröster, Dr. Martin Köhler, and the Neurotar team provide answers to questions from their webinar on long-term imaging of dura mater–transplanted pancreatic islets in awake mice.
Skeletal Muscle Circadian Clocks: Keeping Time for Systemic Health
Dr. Karyn Esser presents the critical role of skeletal muscle circadian clocks in maintaining muscle strength, metabolic health, and systemic adaptations to endurance exercise.
Opening a New Window: Stable Long-Term Imaging of Dura Mater–Transplanted Pancreatic Islets in Awake Mice
Join Drs. Tröster and Köhler as they present a novel dura mater transplantation platform for long-term, anesthesia-free imaging of pancreatic islets in awake mice.
The Expert Approach to Preclinical Indirect Calorimetry Experiments
Join us to explore the IICCC’s standardized guidelines for preclinical indirect calorimetry, focusing on rigorous data normalization techniques and the integration of multi-modal physiological measurements to ensure experimental reproducibility.
Non CYP Mediated Metabolism Pathways and In Vitro Evaluation Strategies
Discover non-CYP metabolism pathways, key enzymes, and in vitro strategies for safer drug development in this webinar.
Piezo1 Protein: A Key Player in Gut Motility and Inflammation Regulation
Discover how the Piezo1 protein in intestinal neurons influences gut motility and inflammation, offering new insights and potential therapies for conditions like IBD.
The Impact of Nutrition on T Cell Fate and Exhaustion
Researchers at the Salk Institute have discovered that a switch from acetate to citrate as a nutritional source significantly influences T cell identity, particularly transforming active effector T cells into exhausted ones in chronic infections like cancer and HIV.
The Complexities and Risks of Microbiome Interventions for Children
Probiotics, touted for their health benefits, are raising FDA safety warnings and concerns about their use in infants, while regulatory challenges similarly impact fecal microbiota transplants (FMT). Consequently, medical professionals urge caution with probiotics and FMT in vulnerable groups, emphasizing potential risks over benefits.
Metabolic Mechanisms that Contribute to Pregnancy-Induced Cardiac Growth and its Reversal
Dr. Helen Collins answers questions from a recent webinar on cardiovascular changes and risks in healthy pregnancies and her research on metabolic mechanisms behind pregnancy-induced cardiac growth.
Indirect Calorimetry for Rodent Research: New Approaches to Enhance Translational Value
In this webinar, Professors John Speakman and Emma Slack each present research from their labs using the TSE PhenoMaster platform for indirect calorimetry.
Innovative Protein Mapping of Cerebral Spinal Fluid for Early Alzheimer’s Detection
A collaborative team of neuroscientists, biochemists, and Alzheimer's specialists from the United States and Icelandic institutions has developed a protein map to identify early markers for Alzheimer's disease in cerebrospinal fluid.
Clambake: An Algorithm to Decode Energy Expenditure Data from Metabolic Cages
In this webinar, Dr. Jonathan Brestoff discusses his research on metabolism and a new method to quantify metabolic data known as Clambake.
More Than What You Eat: The Regulation of Metabolic Health and Aging by Diet Composition and Activity
Join Dudley Lamming, PhD to learn how the specific composition of dietary protein and exercise influence metabolic health and aging.
Exploring Estrogen’s Role in Metabolism and the Use of 13C-Labeled Nutrients for Advanced Animal Physiology and Nutrition Research
In this Q&A, Dr. Reilly Enos and Dr. Levin answer questions about their research focused on estrogen signaling in obesity and metabolism in insect models, respectively.
Control of Muscle Glucose Uptake in vivo: Thinking Outside the Myocyte
In this webinar, David Wasserman, PhD provides a more complete understanding of muscle glucose uptake through consideration of the integration of physiological systems that control this process.
Exploring Estrogen’s Role in Metabolism and the Use of 13C-Labeled Nutrients for Advanced Animal Physiology and Nutrition Research
Dr. Reilly Enos and Dr. Eran Levin discuss estrogen's metabolic impact and how isotopic labeling and 13C-labeled nutrients can be used for animal physiology and nutrition research.
Impact of Sleep and Circadian Disruption on Human Health and Disease Risk
Join Josiane Broussard, PhD as she explains the links between sleep and circadian disruption and cardiovascular and metabolic health.
Autonomic Regulation of Metabolic and Cardiovascular Functions in Health and Disease
In this webinar, Dr. Rahmouni presents his research on the fundamental processes mediating autonomic nervous system control of energy homeostasis and cardiovascular function in health and disease.
A Breath of Not-So-Fresh Air: the Combined Effects of Air and Noise Pollution
While air and noise pollution have been well documented independently, their combined effects are insufficiently discussed, until recently. In this blog post, we discuss a recent publication from Kuntic et al. on the combined and individual effects of these pollutants in mice.
Talking Real Science with Martin Young
Martin Young shares his career path, background, and the influence and guidance he has received from through generations of scientific mentorship.
Talking Real Science with Martin Young
This episode of Share Science features Dr. Martin Young, a professor of medicine at the University of Alabama at Birmingham. In this interview he shares his journey into cardiac metabolism and chronobiology as well as some notable mentors that helped him along the way.
The Blues & the Browns: Links between Depression and Gut Microbiota
Recently, Radjabzadeh et al., identified 13 genera of gut microbiota that have been implicated with symptoms of depression.
#ExpertAnswers: Dudley Lamming on the Influence of Sex and Genetic Background on Diet
Dudley Lamming, PhD, explains that “We Are More Than What We Eat”; Sex and Genetic background are important factors in observing responses to diet in mice.
