Skeletal Muscle Circadian Clocks: Keeping Time for Systemic Health
Dr. Karyn Esser presents the critical role of skeletal muscle circadian clocks in maintaining muscle strength, metabolic health, and systemic adaptations to endurance exercise.
Advancing Sarcopenia Research: CUHK Lab Unveils Early NMJ Deficits in Aging with Aurora Scientific’s 1200A
Professor Louis Cheung's lab at CUHK studies sarcopenia—the age-related loss of muscle mass—by pioneering interventions like vibration therapy by utilizing instruments including the Aurora Scientific 1200A system to precisely quantify neuromuscular junction (NMJ) dysfunction. Watch this interview to learn more about these advancements.
Building Bridges in Muscle Research: The Story Behind AMB’s Innovative Approach and Partnership with Aurora Scientific
In this interview, we sit down with Anthony Hessel and Khoi Nguyen, co-founders of Accelerated Muscle Biotechnologies (AMB), alongside Chris Rand from Aurora Scientific, to explore how their partnership is shaping the future of muscle research.
Redox Regulation of Skeletal Muscle: A Journey from Liverpool to the International Space Station
Dr. Anne McArdle and Dr. Malcolm Jackson explore groundbreaking research from the Muscle Laboratories at the University of Liverpool. They examine how redox regulation influences the adaptive responses of skeletal muscle during physical activity and how these processes evolve with age.
Innovative Brain Map Uncovers Potential Key Players in Multiple Sclerosis Progression
Researchers at the NIH have created a 4D brain map using a marmoset model to uncover early lesion development in multiple sclerosis, potentially advancing treatment strategies and understanding of brain injuries.
Effects of Ovarian Failure on Muscle Form and Function
In this presentation, Parastoo Mashouri, PhD Candidate will explore her pioneering research on the effects of gradual ovarian failure on skeletal muscle function.
Molecular Signals Mediating Increases in Muscle Size and Function
Bert Blaauw answers questions from a recent webinar on skeletal muscle regulatory pathways and the resulting changes in muscle size and function.
Out of This World Research at Brock University: Post Mission Insights into Alterations of Soleus Muscle Function in Space-Flown Mice
Hear Dr. Val Fajardo, Jessica Braun, and Briana Hockey on their experience working on NASA's Rodent Research-20 (RR-20) mission at the Roskamp Institute, the data collected utilizing Aurora Scientific equipment, and future directions of the lab.
Molecular Signals Mediating Increases in Muscle Size and Function
In this webinar, Dr. Bert Blaauw elucidates skeletal muscle regulatory pathways and offers approaches to tackle muscle deficits for therapy.
Pressure-Volume (PV) Loops: Overview and Applications
PV loops are widely used among cardiovascular researchers as well as countless other disciplines, but there seems to be a lack of educational resources about them. Here we dive into what PV loops are, when they are used, as well as some case studies and limitations.
#ExpertAnswers: Christopher Perry and Homira Osman on Integrating Patients, Clinical, and Advocacy Partners with Preclinical Research Labs
Dr. Christopher Perry, York University and Dr. Homira Osman, Muscular Dystrophy Canada answer questions from a recent webinar on how the integration of clinical, industrial, and not-for-profit advocacy partners with preclinical research labs offers great potential to improve our research impact.
Unlocking Heart Health: Revolutionizing Diastolic Function through Integrative Muscle Physiology at Wayne State University
Dr. Charles Chung is an Associate Professor of Physiology at Wayne State University. Using integrated physiology, analyzing data from the molecular level to the whole muscle, his laboratory aims to provide new directions and identify novel treatments for a variety of cardiac disorders. Learn more about his research group by watching the interview or summarized blog below.
Out of This World Research at Brock University: Space Flight’s Impact on Female Mice Reproductive Health
NASA's SpaceX CRS-29 launched on November 9th, a commercial resupply services mission to the International Space Station (ISS) that was also carrying scientific experiments and technology demonstrations. Included amongst these was the Rodent Research-20 (RR-20) payload, the contents of which will be studied by Brock University's Dr. Val Fajardo and his team using Aurora Scientific equipment upon its return.
Control of Muscle Glucose Uptake in vivo: Thinking Outside the Myocyte
In this webinar, David Wasserman, PhD provides a more complete understanding of muscle glucose uptake through consideration of the integration of physiological systems that control this process.
Cut and Paste of Myosin Binding Protein-C in Striated Muscles
Dr. Samantha Harris discusses the development of three new mouse models in her lab, engineered to target and replace specific myosin binding protein-C paralogs in muscle fibers and impact of their mutations on skeletal and cardiac muscle diseases.
Integrating Patient Engagement and Trainee Development in Pre-Clinical Research
Christopher Perry, PhD discusses how his laboratory aims to discover mechanisms by which metabolic dysfunction causes muscle weakness and apply these findings to develop new therapies for muscle disorders. Homira Osman, PhD provides a particular focus on leveraging scientific findings for practice and policy and linking trainees with patient communities.
What Does Exercise Do for the Brain?
While the overall benefits of exercise have been well documented, what exactly does exercise do for the brain? In this blog, we review two very recent publications that arrived at somewhat conflicting answers to this question.
How High-Impact Sports Affect Brain Health: Chronic Traumatic Encephalopathy (CTE)
Chronic Traumatic Encephalopathy (CTE) is a condition that arises from repeated head traumas, and can only be diagnosed after death. Learn more about the history behind this condition, current research, and potential ways to prevent CTE in this blog post, written by one of the Scientist.com STEM NIL Scholarship Winners.
Video Interview – Aurora Scientific’s 801C: Small Intact Muscle Apparatus
Chris Rand discusses Aurora Scientific's 801C: Small Intact Muscle Apparatus. The device can be used for measuring muscle contractility and for other applications in fields like muscle physiology and cardiovascular science research.
How Aurora Scientific is Empowering the Research Community: An Interview with General Manager Matt Borkowski
InsideScientific recently interviewed Matt Borkowski, General Manager of Aurora Scientific, where he discussed his new role, the company's approach to innovation, and commitment to providing customer support through educational resources.
Functional Recovery of the Musculoskeletal System Following Injury – Leveraging the Large Animal Model
Sarah Greising, PhD answers top questions from her recent webinar focused on the pathophysiologic understanding of the skeletal muscle remaining following traumatic musculoskeletal injuries, specifically in large animal models.
Cardiac Tissue Slices: Preparation, Data Acquisition, and Analysis
Bradley Palmer, PhD, answers top questions from a recent webinar on the challenging preparation of cardiac tissue slices and measurement of force and calcium.
#ExpertAnswers: Sarah Greising on Muscle Injury Recovery
Sarah Greising discusses the current pathophysiologic understanding of the skeletal muscle remaining following traumatic musculoskeletal injuries.
#ExpertAnswers: Bradley Palmer on Measuring Cardiac Tissue
Bradley Palmer answers questions from a recent webinar where he highlighted and demonstrated the challenging preparation of cardiac tissue slices and measurement of force and calcium.
Mitochondrial Adaptations and Homeostasis: Student Research from the MHRC
The Muscle Health Research Centre (MHRC) is one of Canada's leading innovators in muscle physiology research. In this blog post, we finish our series of interviews with student researchers at the MHRC and learn more about their research objectives, findings, and goals.
