Dr. Cui Can is a postdoctoral fellow in the Department of Orthopaedics and Traumatology at The Chinese University of Hong Kong. The research focuses on musculoskeletal regeneration and neurophysiological degeneration, with an emphasis on addressing musculoskeletal aging issues, particularly sarcopenia.

Dr. Cui’s research has found that the degeneration of neuromuscular junctions precedes the onset of sarcopenia during aging. Low-magnitude high-frequency vibration (LMHFV) therapy can mitigate the progression of muscle degeneration in SAMP8 mice with sarcopenia. Further studies indicate that muscle inflammation and macrophage polarization play a major role in the differentiation of skeletal muscle stem cells, leading to sarcopenia-related skeletal muscle dysfunction.

Clinically, Dr. Cui’s main research involves using single-fiber electromyography (SFEMG) as a new diagnostic method for sarcopenia. Over the past few years, she has published several articles on sarcopenia in top journals such as *Aging Cell*, *Journal of Cachexia, Sarcopenia and Muscle*, *Ageing Research Reviews*, and *Journal of Orthopaedic Translation*. In 2023, Dr. Cui received funding as a principal investigator from the Health and Medical Research Fund Research Fellowship (HK$1,003,990) and the IdeaBooster Fund (CUHK, HK$150,000). Dr Cui have also participated in numerous research grants, including the Areas of Excellence (HK$70.688M), Collaborative Research Fund (CRF, HK$4,772,807), General Research Fund (GRF, HK$1,160,548), and direct funding from CUHK. Additionally, Dr Cui have received the Best Research Paper Award from the Department of Orthopaedics and Traumatology at CUHK for PhD thesis on the effects of oral magnesium supplementation on age-related muscle degeneration in sarcopenia.