Expert Answers Archives

#ExpertAnswers: Anilkumar K. Reddy on Noninvasive Blood Flow Velocity Measurements

Anilkumar K. Reddy discusses noninvasive blood flow velocity measurements to quantify changes in hemodynamics and characterize cardiac disease without the need for complex surgery or imaging.

#ExpertAnswers: Trevor Day on the Effects of Tilt, Exercise and High Altitude

Trevor Day discusses the effects of tilt, exercise and high altitude on human cardiorespiratory and autonomic nervous systems.

#ExpertAnswers: John Cockroft and Coleman Bessert on Biomechanics

John Cockroft and Coleman Bessert discuss biomechanics, specifically kinematics, kinetics and neuromuscular activation.

#ExpertAnswers: José Gadea on Implantable Pumps

José Gadea discusses the use of implantable pumps as an alternative to serial injections when administering compounds to laboratory animals.

#ExpertAnswers: Brian Roche and Jason Payseur on Studying Multiple Biological Systems

Brian Roche and Jason Payseur discuss how to integrate hemodynamic, respiratory and neurological measurements to study multiple biological systems simultaneously while benefiting from more efficient data collection and workflow in the laboratory.

#ExpertAnswers: Mads Kjølby and Niels Wellner on Food and Water Intake of Rodents

Mads Kjølby and Niels Wellner discuss the latest technology and best practices for studying food and water intake as well as feeding kinetics of group-housed rodents in their home cage.

#ExpertAnswers: Hasan Ayaz, Frazer Findlay and Kurtulus Izzetoglu on the Fundamentals of fNIRS

Experts discuss the fundamentals of fNIRS and present research capabilities enabled through the integration of optical brain imaging technology and physiological recording systems.

#ExpertAnswers: Julie Gill and Matt Croxall on Cognitive Evaluation of Rodents

Julie Gill and Matt Croxall discuss the methodology and best practices of Bussey-Saksida Touchscreen Systems used for the cognitive evaluation of rodents.

#ExpertAnswers: Charles Vorhees and Jason Adair on Reflex Testing in Rodents

Charles Vorhees and Jason Adair discuss best-practices and prescribed techniques for Acoustic, Tactile and PPI (Pre-Pulse Inhibition) paradigms for startle reflex testing in rodents.

#ExpertAnswers: Seth Hays and Drew Sloan on Forelimb Function in Rats and Mice

Seth Hays and Drew Sloan discuss quantitative measurements with automated, high-throughput systems in rodent models.

#ExpertAnswers: Róbert Kovács on Social Behavior in Zebrafish

Róbert Kovács discusses novel methods for quantitative characterization of zebrafish social interactions and locomotor activity.

#ExpertAnswers: Éric Thorin on Flow-Induced Dilation

Éric Thorin discusses flow-induced dilation in isolated blood vessels using pressure myography.

#ExpertAnswers: Peter Lundh von Leithner on Eye Function

Peter Lundh von Leithner discusses the application of electroretinography in rodent in vivo research studies as a method to better understand and characterize eye function.

#ExpertAnswers: Meike Mischo, Frazer Findlay, and Arnd Rose on Integrating Eye Tracking Data

Meike Mischo, Frazer Findlay and Arnd Rose discuss gaze behavior measurements with physiological monitoring in both screen-based and interactive, mobile applications.

#ExpertAnswers: Henry Holzgrefe and Belal Mohamed on Arrhythmia Detection

Henry Holzgrefe and Belal A. Mohamed discuss arrhythmia detection and improving data analysis in the preclinical research setting.

#ExpertAnswers: Robert Doyle on Novel Drug Delivery Methods

Robert Doyle discusses novel drug delivery methods for basic research, drug discovery and development.

#ExpertAnswers: Jacqueline Phillips and Fiona McBryde on Telemetry Measurements in Rats

Jacqueline Phillips and Fina McBryde discuss telemetry measurements in rat models of cardiovascular integrative physiology and neurophysiological research.

#ExpertAnswers: Christian Schnell on Drug Delivery Methods

Christian Schnell discusses novel drug delivery methods for basic research and novel infusion technologies.

#ExpertAnswers: Jim Georgakopoulos on Pressure Volume Catheter Calibration

Dr. Jim Georgakopoulos discusses the parameters of ventricular pressure-volume catheter calibration.

#ExpertAnswers: Ralf Dechend & Christian Schnell on Continuous Glucose Monitoring in Rodents

Ralf Dechend and Christian Schnell discuss collecting a complete glucose profile via implantable telemetry.

#ExpertAnswers: Chris Lloyd on Automated Video Tracking

Chris Lloyd discusses the application of automated video tracking in behavior studies.

#ExpertAnswers: Rob Grange & Matt Borkowski on Isometric Twitch

Rob Grange and Mathew Borkowski discuss the characterization of complete muscle function by combining, lengthening, shortening and isotonic contraction tests with traditional isometric twitch and tetanus measurements.

#ExpertAnswers: Timothy Hacker and Filip Konecny on Pressure-Volume Loop Data

Timothy Hacker and Filip Konecny discuss best practices and methods for accurate and repeatable collection of pressure volume data in large animal models of cardiac dysfunction and heart disease.

#ExpertAnswers: Charles Meshul, Carolanne Milligan, and Tom Hampton on Gait Analysis

Charles Meshul, Carolanne Milligan, and Tom Hampton discuss methodology, best practices, and techniques for identifying early and subtle quantitative physiological markers of strength, balance, and coordination in animal models of pain, CNS, neuromuscular, and neurodegenerative disorders.