humanized mice Archives

Beyond Checkpoints: Strategic Use of CDX Models in Emerging IO Therapies

liamisc2025-11-11T16:41:17-05:00Cancer & Oncology Research, Cell & Molecular Biology, Drug Discovery & Development, Microbiology & Immunology|

Learn how enhanced CDX models with humanized immune systems improve preclinical-to-clinical success in emerging immuno-oncology therapies.

Applications of Humanized Mice in the Evaluation of Antibody-Drug Conjugates to Treat Autoimmune Diseases

liamisc2025-01-03T13:36:47-05:00Cell & Molecular Biology, Drug Discovery & Development, Lab Animal Sciences, Microbiology & Immunology|

Join experts from GemPharmatech and BioRay Pharmaceutical as they discuss the use of humanized mice to evaluate antibody-drug conjugates for treating autoimmune diseases.

#ExpertAnswers: Michael Czech on CRISPR-Enhanced Adipocyte Browning

In this episode of Expert Answers, Dr. Michael Czech discusses a novel CRISPR-based cell therapy which enhances adipose tissue "browning" as a treatment for metabolic disease.

CRISPR-Enhanced Adipocyte Browning: A Cell Therapy Approach to Treat Metabolic Disease

liamisc2022-03-31T13:13:05-04:00Cardiovascular, Cell & Molecular Biology, Metabolic Function, Obesity, Preclinical Imaging|

Michael Czech, PhD discusses adipose tissue "browning" as a treatment for metabolic disease, and presents recent data using light sheet microscopy to visualize functional changes in adipose tissue depots.