Approaches to Studying Neuronal Signaling in the Brain of Awake Behaving Mice
In this Mandarin-language webinar, Dr. Freddy Yan discusses head-fixed and head-mounted approaches to recording neuronal activity in awake, behaving mice.
Cutting Edge Conversations: Innovative Approaches to Chemistry, Manufacturing and Controls
Episode 4 in the Cutting Edge Conversation series featured Dr. Mujeebur Rahuman, Dr. Holger von Moeller, and Dr. Fernando Huerta as they discuss about industry challenges and innovations surrounding Chemical, Manufacturing and Controls in the life sciences industry.
Translational Science Panel: Research Insights and Best Practice for Clinical Relevance
Join Aaron Phillips, Fiona McBryde, and Kevin O'Gallagher for a 1-hour Translational Science panel.
Examining the Anatomy and Physiology Lab Experience
Join Wendy Riggs for a deep dive into the virtual Anatomy and Physiology Labs that she runs at College of the Redwoods and how she uses technology to facilitate meaningful learning opportunities for her students.
Cutting Edge Conversations: Value, Access and Evidence – Biotech Market Access
Sajjad Raza, Steven Fountain, and Sonya Snedecor present in Episode 2 of Scientist.com's Cutting Edge Conversations series with a presentation on the challenge research manufacturers face when they need to maximize access for patients with payers. The many considerations for a biotechnology company during various phases of drug development and how companies could use efficient sourcing strategies for market access.
Cutting Edge Conversations: Challenges in Sourcing Human Biosamples
Richard Kondo, McLean Collins, and Cathie G. Miller highlighted Episode 3 of the Cutting Edge Conversations series focused on innovations in the area of sourcing human biosamples for research. The event focused on sourcing human samples for research, including the value and necessity of working with human tissue during drug discovery, as well as some of the distinct challenges researchers face.
Electrophysiology of Human Native Receptors in Neurological and Mental Disorders
Dr. Agenor Limon presents research integrating functional metrics with large anatomical, transcriptomic, and proteomic datasets to evaluate the relationship between synaptic E/I ratio and behavioral abnormalities across postmortem intervals and brain banks.
Respiration in Anesthetized Mice: Evidence-Based Recommendations for Improved Monitoring & Supportive Care
Join Dr. James Marx as he discusses improving the care and use of mice in biomedical research, with a focus on the pharmacology behind the effects of anesthetics on respiration.
AcuiSee – Rodent Visual Acuity Using Behavioral Conditioning
Dr. Jeff Jamison presented on the connection between operant conditioning and studying vision in small animals, and how visual acuity tasks can form the basis for various research models, including toxicology and pharmacological testing.
How Transformative Antibody Technology Can Improve Your Bioanalytical Assays
Dr. Royle discusses how the combination of antibody phage display and SpyTag technologies can generate critical antibody reagents with a difference.
Translational Applications of MiniPDX: An In Vivo Organoid Assay in New Drug R&D
Join Dr. Danyi Wen as she describes a novel drug efficacy test using Patient Derived Xenograft (PDX) samples to measure drug efficacy and identify therapeutic candidates in personalized oncology treatments.
Advanced MicroCT for Non-Destructive 3D Multiscale Analysis
Experts provide a tour of academic and industrial use cases in Materials Science, Engineering and Life Science.
Particulate Contamination in Medical Devices and Single-Use Systems
Join Mark Bumiller as he discusses the importance of subvisible particulate testing and provides an overview of solutions from Entegris to meet the qualification requirements.
Functional Ultrasound Neuroimaging in Awake & Behaving Non-Human Primates
Dr. Pierre Pouget and Dr. Serge Picaud provide an overview of fUS imaging and discuss how it can be used to study the brain in behaving non-human primates.
Using Chemical Denaturants and Light Scattering to Determine Aggregation Propensity of Biopharmaceuticals
Dr. Luke Holloway reviews light scattering-based methods for protein characterization and explains their utility, when combined with partially denaturing buffers, in understanding aggregation propensity of monoclonal antibodies.
Musculoskeletal Complications of Cancer and its Treatments
Dr. Andrea Bonetto discusses the importance of musculoskeletal preservation in cancer treatment and shares evidence that bone preservation directly impacts muscle size and function in cachexia.
Plasma Proteomics: The Next Frontier of Biomarker Discovery in the Precision Medicine Era
Plasma proteomics is increasingly recognized as a fundamental approach to accelerate biomarker discovery and drug development, taking precision medicine to the next level.
Reduce pH Measurement Errors
Dr. Urs Hartfelder offers insights on how to reduce or prevent pH measurement errors.
More Than Meets the Eye: Flavor Perception, Facial Expression Analysis, and Predicting Food Choice Behavior
Join Jason Rogers, PhD and Geertje van Bergen, PhD as they take us on a sensory deep dive into flavor perception, facial expression analysis, and food choice and consumption behavior.
Continuous Glucose Monitoring and Glycemic Variability in Pregnancy
Join Caroline Wuyts, MSc for a deep dive into her research on pregnancy and monitoring glucose availability throughout the reproductive timeline of a mouse model.
Simultaneous Multi-Region Neuronal Calcium Imaging in Freely Behaving Subjects
Dr. Yasaman Soudagar and Dr. Roshni Christo demonstrate how to use calcium imaging in up to 4 implanted areas of the brain of freely behaving mice to map out neuronal circuits and identify changes that take place under different disease conditions and behavior mechanisms.
IR Photorefraction and IR Photokeratometry – Measuring Refractive State and Corneal Curvature in Animals and Humans
Prof. Frank Schaeffel discusses the optical principles, image processing algorithms, calibration, and potential pitfalls within IR photorefraction and IR photokeratometry.
Fast Scanning Chip Calorimetry
Dr. Jürgen Schawe discusses why fast scanning chip calorimetry is the ideal complement to conventional DSC with heating and cooling rates now covering a range of more than 7 decades.
Cutting Edge Conversations: The Role of In Vivo Studies in Personalized Medicine
Grace Walton, Jonathan Nakashima, and Meghan Loy kick off Episode 1 of Scientist.com's Cutting Edge Conversations series with a presentation on fundamentals and future trends around the role of in vivo studies in personalized medicine
Cerebral Open Flow Microperfusion (cOFM) for in vivo Cerebral Fluid Sampling – Comparison of cOFM and Microdialysis
Dr. Joanna Hummer and Dr. Florie Le Prieult share insights into cOFM's use and utility in the broader neuroscience field and specifically for the development of drugs for neurodegenerative diseases.
