Improving Confidence in Thyroid Hormone Disruption Assessment Using a Novel Human-Relevant In Vitro Model
Learn how an emerging NAM is helping advance more efficient, human-relevant strategies for assessing thyroid hormone disruption while reducing reliance on animal testing.
Photoreceptor Cell Therapy to Treat Advanced Retinal Degeneration
Dr. Rachael Pearson explores how transplanting human stem cell-derived cone photoreceptors can functionally restore vision and light-evoked behavior in cases of advanced retinal degeneration.
Novel Applications of the Cellular Thermal Shift Assay (CETSA) Provide New Insights for Drug Discovery
Join AbbVie scientists Shitalben Patel and Jami R. Erickson as they showcase their innovative advancements, transforming CETSA® into a high-throughput flow-based platform and introducing new whole blood formats to elevate drug discovery.
Improved Clearance Predictions for Aldehyde Oxidase Substrates Using TruVivo, a Novel Human Hepatocyte Model
In this exclusive session, Stephanie Piekos, PhD, Senior Scientist at Boehringer Ingelheim, shares insights into the challenges of evaluating AO substrates and how more predictive, human-relevant models are shaping the future of DMPK studies.
Innovative Approaches to Assessing Thyroid Disruption: The 3D Human Thyroid Microtissue Model
Dr. Chad Deisenroth, PhD, from the US EPA, introduces an advanced human in vitro 3D thyroid microtissue model designed to evaluate thyroid hormone disruption, addressing current challenges with existing models.
Evaluation of TruVivo, an All-Human Hepatocyte Model for Mechanistic DMPK Investigations
Join Diane Ramsden, PhD, and Lindsey Whaley, MS, for an inside look at TruVivo™, a novel all-human in vitro hepatocyte system developed by LifeNet Health LifeSciences.
#ExpertAnswers: Edward LeCluyse and Paul Gallant on a Novel Hepatic Triculture System
Edward LeCluyse and Paul Gallant discuss their novel all-human hepatic triculture system including its benefits and applications.
A Novel, All-Human Hepatic Triculture System
Join Edward LeCluyse and Paul Gallant as they offer insight into a novel, all-human hepatic triculture and how this unique system addresses the need for a convenient and human-relevant long-term hepatic culture.
