Initial Orthostatic Hypotension: Don’t Blink or You Will Miss It
Join Dr. Satish Raj and Nasia Sheikh for an overview of Initial Orthostatic Hypotension (IOH), how these patients present in the clinic, the mechanisms that underly the condition, and how IOH can be managed with a non-pharmacological approach.
Antibody Discovery Platforms to Support Functional Monoclonal Antibody Generation
Join Dr. Jiahui Yang as she provides an overview of antibody discovery platforms and discusses how single B cell sorting can be used to generate functional monoclonal antibodies for a range of applications.
Quantifying Cardiovascular and Behavioral Correlates of Fear in Mice: Implications for PTSD and Cardiovascular Disease Risk
Dr. Paul Marvar and Benjamin Turley present research pairing behavioral and cardiovascular responses to cued fear learning and demonstrate how fear-based disorders (such as PTSD) can contribute to cardiovascular disease risk.
Cardiac Effects of Chronically Inhaled Nicotine
Dr. Jason Gardner presents his recent and exciting new findings on the long-term cardiopulmonary health effects of inhaled nicotine including preclinical evidence to treat these health impacts.
Metabolic Adaptations: The Physiology of Cold Acclimatization and Exercise in Rodent Models
Join Jonas Treebak, PhD and Alexander Bartelt, PhD for a deep dive into the physiological mechanisms underlying metabolic adaptations to exercise training and cold exposure.
Cardiac Glucose Metabolism: Heart Failure in Diabetes and Aging
Join Dr. Dale Abel for a deep dive into the mechanisms underlying heart failure in aging and diabetes.
Sex, Drugs and Protocol: How Researcher Choices Impact Experimental Outcomes in Preclinical Diabetes Research
Aileen King presents data showing that small alterations to experimental protocol and choice of model can impact on both welfare and data interpretation when studying blood glucose homeostasis in mice.
Streamlining Process Monitoring in Cell Culture Analysis & Spectrometry
Daniel Merriman, Femi Egbebi and Krzysztof Inglot discuss research solutions offered by Thermo Fisher Scientific regarding cell culture analysis, spectrometry and other topics within the biopharma field.
Echolocation with Light: A New Form of Active Sensing in Fish?
Prof. Nico K. Michiels discusses how weak light reflections, during active photolocation, in the pupils of predator and prey species can be strong enough to be perceptible by the initial light sender.
Biodegradable Long-Acting Injectable Implants Prepared By Hot Melt Extrusion
Join Dr. Thanh Nguyen for a presentation on injectable implants developed using twin-screw extrusion, an upcoming technology in pharmaceutical manufacturing.
Old Dogs Benefit From New Tricks: 3D Analysis of Arterial Injury to Study Nrf2-Dependent Inhibition of Neointimal Hyperplasia in Rats
Edward Bahnson, PhD presents the development and validation of a methodological approach using light-sheet fluorescence microscopy (LSFM) for the imaging of preclinical models of vascular injury with a focus of minimizing analysis bias while increasing precision and reproducibility.
Autonomic Dysfunction in Long-COVID
During this webinar, experts from Imperial College Healthcare NHS Trust describe the presenting symptoms and diagnostic challenges for patients in their syncope clinic presenting with autonomic dysfunction in Long-COVID.
Improving Sleep to Slow the Progression of Alzheimer’s Disease
Join Rohan Jagirdar, PhD as he discusses his research on EEG activity in a mouse model of Alzheimer's disease to determine the effects of improved sleep on disease progression.
EEG Monitoring Approaches to Predict Learning and Memory Changes in Early Alzheimer’s Disease
Dr. Fiona Harrison discusses how dietary deficiency and exposure to toxins can impact glutamate uptake and clearance, and the subsequent changes in neural signaling can be detected through altered EEG activity and performance on learning and memory tasks.
Sensorimotor Network Development During Early Postnatal Life in the Awake and Sleeping Brain
Dr. Anna Cavaccini and Dr. James Dooley share insights into the development of rodent sensorimotor neuronal circuits during early postnatal life.
Assessing Neuroinflammation-Related Neural Damage by Monitoring the Retinotectal System
Dr. Janos Groh discusses how neuroinflammation amplifies neural damage and disease outcome in models of various disorders, and the value of monitoring the retinotectal system to assess neural disease progression and associated treatment efficacy.
Remodeling of Pancreatic Innervation in Diabetes
Dr. Sarah Stanley and Dr. Alexandra Alvarsson discuss the use of whole-organ assessment for the comprehensive examination of pancreatic innervation, revealing close interactions between nerves and islets and dynamic regulation of islet innervation in diabetes.
Telemetry 101: Exploring the New ADInstruments’ Small Animal Telemetry Systems
Join Phil Griffiths, PhD for a technology overview and discussion around popular and unique applications of Kaha Telemetry for small animal research.
Ecophysiological Impacts of Climate Change: Performance, Fitness and Extinction
Join Caroline Williams, PhD and Eric Riddell, PhD as they discuss their research involving climate change and the ecophysiological effects of changing global temperatures on organismal biology and survival.
Spectronaut: Expand Biological Insights with DIA Proteomics
Data-independent acquisition (DIA) has become the method of choice for large-scale discovery proteomics. Its application for single-cell analysis promises to be more sensitive, robust, and reproducible than other proteomic approaches but is still a fairly unexplored territory.
Synchronous Tracking of Oxygen Saturation in Vital Organs: The Effects Beyond Heart Failure
Join Dr. Sicard for an examination of the systemic effects of myocardial infarction using high-frequency ultrasound and photoacoustics.
Compound Delivery, PK-PD, & Validation Studies in Oncology Research
Dr. Christian Schnell describes his work involving implantable infusion pump studies in rodents and the advancement of pharmacological interventions in oncology research.
Unraveling Excitation-Contraction Coupling: Simultaneous Measures of Intracellular Calcium and Action Potentials
Join Patrick Schönleitner, PhD and Francisco Altamirano, PhD as they share their work involving simultaneous measurements of intracellular calcium, membrane voltage, and contractility of cardiomyocytes.
Quality, Quantity and Timing: Regulating Healthspan and Lifespan With Diet
Join Dudley Lamming, PhD for a deep dive into his research involving how diets can affect metabolic health and longevity.
Evaluation and Optimization of Right Ventricular and Lung Imaging Using High Frequency Ultrasound
Allison Rodgers discusses the value of imaging the mouse right ventricle and lungs using high-frequency ultrasound for models of cardiopulmonary physiology and associated diseases.
