Reprogramming Mouse Fibroblasts Into Induced Cardiomyocytes: Age-Related, Metabolic, and Epigenetic Barriers
Join Dr. Sandrina Nóbrega-Pereira as she discusses the role of age, epigenetics, and mitochondrial metabolism in the Direct Cardiac Conversion (DCC) of fibroblasts into induced cardiomyocytes (iCMs).
Photoacoustic Imaging in Angiotensin II Induced Cardiac Hypertrophy Mice
Hear Dr. Emily Lupton on her lab's investigation whether photoacoustic imaging (PAI) could provide novel imaging in the heart after angiotensin-II induced hypertrophy with and without treatment with losartan.
Cut and Paste of Myosin Binding Protein-C in Striated Muscles
Dr. Samantha Harris discusses the development of three new mouse models in her lab, engineered to target and replace specific myosin binding protein-C paralogs in muscle fibers and impact of their mutations on skeletal and cardiac muscle diseases.
From Models to Heartbeats: Computational Design of Vagus Nerve Stimulation for Cardiac Health
This webinar explores closed-loop cardiac rhythm control restoration in heart-transplant patients from model development to in silico regulatory evidence for safety and efficacy trials.
Measurement of Cardiac Function Using Pressure-Volume Loops in Swine
Dr. Pedro Ferreira gives a deep dive into his work using pressure-volume loops in large animal models of heart failure.
Can the Immune System Protect after Repeated Myocardial Injury?
While the immune response to a single cardiac event has been well researched, few have reported on whether an adaptive immunity is observed after repeated cardiac injury. Here, we discuss a recent publication from Tiwary et al., in which they investigate the cytoprotective response after multiple cardiomyopathic injuries.
#ExpertAnswers: Martin Young on Nutrient Intake Cycles and Metabolism
Martin Young discusses how 24-hour circadian rhythms and metabolism affect cardiovascular function.
Fine Tuning Nutrient Intake Timing for Cardiac Health
Martin Young discusses 24-hr circadian rhythms that influence processes like metabolism that are critical to cardiovascular function.
