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Combination Therapy for Cancer Treatment
The combination of anti-cancer drugs, or combination therapy, has been hailed as a “cornerstone of cancer therapy” since it targets key pathways synergistically, thereby enhancing efficacy compared to monotherapies. This blog takes a look at a recent publication in Nature, which reported the effects of 2025 pairwise drug combinations in breast, colon, and pancreatic cell lines.
Discovering a Novel Therapy for Urinary Tract Infections
Originally published on Scientist.com, this article provides an overview of antimicrobial therapies, antimicrobial resistance, and advantages of in silico methods for drug discovery.
Inhalable COVID-19 Vaccines: Recent Findings and Breakthroughs
Given that SARS-CoV-2 is primarily transmitted through respiratory droplets, with respiratory mucosa being the main viral entry route, is intramuscular administration the most effective vaccine delivery method to fight COVID-19? In this blog post, we have reviewed one recent study that reported the design and preclinical testing of an inhalable, exosome-based COVID-19 vaccine.
Does Diabetes Promote COVID-19, or Does COVID-19 Promote Diabetes?
During the COVID-19 pandemic, many of those living with diabetes were required to follow strict guidelines to protect themselves against infection as they were at high risk of morbidity and mortality. This blog takes a look at the links between angiotensin-converting enzyme 2 (ACE2) expression and diabetes, as well as incident diabetes and long COVID.
Cell Painting: The Colorful Future of Drug Discovery
A panel Q&A originally published on Scientist.com that introduces cell painting and highlights its value in preclinical and early drug discovery programs.
Alzheimer’s Disease: Recent Research & Therapeutic Advances
A review of Alzheimer's disease pathology, conventional treatments and their limitations, as well as emerging and potential therapies including monoclonal antibodies, metabolic therapies, and stem cell therapies.
Real-World Data for Mental Health – Understanding Outcomes and Unlocking Pathways to More Precise Treatments
Real-World Data for Mental Health – Understanding Outcomes and Unlocking Pathways to More Precise Treatments OM1 was founded by a team dedicated to the belief that participating in value-based healthcare requires a much more complete view of patient outcomes than what has been available until now. Therefore, [...]
Unlocking the Value of Real-World Data to Provide Real-World Care
Unlocking the Value of Real-World Data to Provide Real-World Care For this tHEORetically Speaking video interview, Mary Tran, MS, from Syapse provided a deep dive into the strengths, weaknesses, and challenges of real-world data (RWD). Syapse is well-known as a real-world evidence (RWE) company, but they are also [...]
Differentiate Your Product From the Competition: Give Payers the Insights They Need
Differentiate Your Product From the Competition: Give Payers the Insights They Need In this competitive pharmaceutical market access landscape, payers are preparing budgets and financial forecasts well ahead of product launches, meaning they require product information earlier and earlier in the pre-approval stage. Patti Peeples, PhD [...]
Recent Advances in Anti-Obesity Pharmacological Research
A review of current obesity treatments and their limitations, the need for animal models in obesity research, and emerging anti-obesity medications including incretin-based therapies, mitochondrial uncouplers, and various phytochemicals.
Women in STEM: Celebrating Our Incredible Female Presenters
Here at InsideScientific, we are fortunate to work very closely with intelligent, talented women in the fields of neuroscience, cardiovascular research, muscle physiology, immunology, metabolic function and obesity, pharmacology, cancer, and respiratory science. In honor of International Women's Day, we would like to not only recognize these incredible presenters, but also celebrate their immense successes and contributions to their respective fields.
Milestones and Recent Advances in HIV Research
In honor of World AIDS Day, InsideScientific has set out to provide information on the historical significance of HIV and AIDS, recent advances in anti-HIV therapy, and the impact that COVID-19 has had on HIV testing, diagnosis and treatment around the world.
Noldus Early-Career Software Grant
Noldus Early-Career Software Grant Noldus Information Technology is seeking proposals from North American researchers from all disciplines of behavioral science research. In particular, Noldus seeks to support outstanding scientific research and career development of scientists at the early stage of their professional careers by providing access to our [...]
Alzheimer’s & Brain Awareness Month 2020
Image source: Alzheimer’s Association @alzassociation June is Alzheimer’s and Brain Awareness Month! At InsideScientific, we are proud to partner with so many researchers and companies who work tirelessly to develop products, conduct research, and advance scientific discovery aimed at curing Alzheimer’s Disease, dementia, and other neurological disorders. The [...]
White Paper – Advancing Cancer Treatments with ALZET® Osmotic Pumps
Success is in the delivery. This white paper from ALZET reviews applications and benefits of osmotic pumps for continuous, precise drug delivery in the context of preclinical oncology research. Although life-saving, drugs that fight cancer usually walk a fine line between therapeutic and toxic. At a low [...]
